Syncope and sudden death in hypertrophic cardiomyopathy

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Syncope and risk of sudden death in hypertrophic cardiomyopathy.

BACKGROUND The prognostic significance of syncope has not been investigated systematically in hypertrophic cardiomyopathy, and treatment strategies have been based largely on intuition and experience. METHODS AND RESULTS We assessed the relationship between syncope and sudden death in 1511 consecutive patients with hypertrophic cardiomyopathy. Unexplained (n=153) or neurally mediated (n=52) s...

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Prevention of Sudden Death in Hypertrophic Cardiomyopathy

C ase presentation: A 14-yearold girl died suddenly and unexpectedly while exercising. Clinical and echocardiographic family screening identified hypertrophic cardiomyopathy (HCM) in her only sibling, an asymptomatic 17-year-old boy. In her brother, echocardiography showed extreme septal ventricular hypertrophy, 35 mm in thickness; left ventricular (LV) outflow obstruction was absent. Left atri...

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Sudden cardiac death risk in hypertrophic cardiomyopathy.

It is well recognized that sudden cardiac death (SCD) is an infrequent, unpredictable, but catastrophic complication of hypertrophic cardiomyopathy (HCM). In population-based studies the overall SCD rate is 1% per year among patients with a clinical diagnosis of HCM. A crucial aspect of the management of patients with HCM is an assessment of each individual patient’s risk for SCD so that preven...

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Sudden cardiac death in hypertrophic cardiomyopathy.

Introduction Hypertrophic cardiomyopathy (HCM) is a common disorder of cardiac muscle associated with sudden cardiac death (SCD). HCM is defined by increased left ventricular wall thickness or mass, in the absence of abnormal loading conditions to account for the observed abnormality. In most adults, the disease is inherited as an autosomal dominant trait and is caused by mutations in cardiac s...

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Syncope in hypertrophic cardiomyopathy.

A patient with hypertrophic cardiomyopathy, syncope, and frequent ventricular tachycardia was monitored during a syncopal episode. An unrecordable blood pressure and the loss of a left ventricular outflow tract murmur without evidence of arrhythmia suggested a primary haemodynamic mechanism such as reduction in left ventricular volume.

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1990

ISSN: 0735-1097

DOI: 10.1016/0735-1097(90)90224-d